Botulinum toxin: The Midas touch

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Botulinum toxin: The Midas touch

Botulinum Toxin (BT) is a natural molecule produced during growth and autolysis of bacterium called Clostridium botulinum. Use of BT for cosmetic purposes has gained popularity over past two decades, and recently, other therapeutic uses of BT has been extensively studied. BT is considered as a minimally invasive agent that can be used in the treatment of various orofacial disorders and improvin...

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The Midas touch?

OBJECTIVE To test the hypothesis that GP trainees are worth their weight in gold. DESIGN Data collected from 100 consecutive patients analysed with reference to practice statistics, fees, and allowances. SETTING General practice, Edinburgh. RESULTS In the year April 1992 to April 1993 the trainee saw 3439 patients, who were worth over 18,000 pounds in capitation fees. The training grant i...

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Point-touch technique of botulinum toxin injection for the treatment of spasmodic dysphonia.

Intralaryngeal injections of botulinum toxin (Botox), under electromyographic guidance, have emerged as an effective treatment for adductor spasmodic dysphonia. To remain effective, these injections must be repeated every 3 to 9 months as the symptoms recur. One drawback to the current method is the need for electromyographic confirmation of needle placement into the thyroarytenoid muscle. This...

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Botulinum toxin and spasticity

The clinical eVects of botulinum toxin have been recognised since the end of the 19th century. It is the most potent neurotoxin known and it is produced by the gram negative anaerobic bacterium Clostridium botulinum. The paralytic eVect of the toxin is due to blockade of neuromuscular transmission. Injection into a muscle causes chemodenervation and local paralysis and this eVect has led to the...

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nondystonic involuntary movements, including those excessive muscle contraction accompanying stroke, demyelinating disease, tremor, and cosmetic condition. Reported benefits in hyperhydrosis has proven that BTX can inhibit overactive non-motor as well as motor peripheral acetylcholine neurons. In addition to reducing muscle hyperactivity and spasm, BTX-A treatment often reduces the pain associa...

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ژورنال

عنوان ژورنال: Journal of Natural Science, Biology and Medicine

سال: 2014

ISSN: 0976-9668

DOI: 10.4103/0976-9668.127274